This article clarifies that aspartame does not contain erythritol, explaining their distinct chemical nature, sources, uses, and safety profiles. Aspartame is a highly sweet artificial sweetener from amino acids, while erythritol is a low-calorie natural sugar alcohol. Emerging studies on erythritol's cardiovascular effects are discussed alongside regulatory approvals. This knowledge helps consumers and manufacturers make informed decisions on sweetener use in foods, beverages, and healthcare products.