This comprehensive analysis compares stevia and sucralose, two popular non-nutritive sweeteners. Stevia, derived from a plant, offers health benefits such as blood sugar regulation and antioxidant effects but can have a bitter aftertaste. Sucralose, a synthetic sweetener, provides a clean, sugar-like taste with high heat stability but raises some concerns about gut health. The article helps consumers and manufacturers balance taste, health, and environmental considerations to choose the best option for their needs.