This article clarifies that sucralose is an artificial sweetener chemically derived from sugar and is approximately 600 times sweeter without calories, while Splenda is the branded product containing sucralose plus bulking agents. It explores their history, uses in food, beverages, and healthcare, discusses safety and culinary properties, and answers common questions, helping producers and consumers understand these sweeteners' important roles in health-focused solutions.

This article explores whether sucralose, a popular artificial sweetener, affects gut health. While animal studies show sucralose may disrupt gut bacteria and promote inflammation, human evidence remains inconclusive. Readers learn about current research, potential risks, and safer sweetener alternatives for gut health.