Sucralose is a widely used artificial sweetener increasingly shown to pose health risks, including DNA damage, gut disruption, inflammation, metabolic and reproductive harms, and cancer risk, particularly when heated. It is advised to limit intake and consider natural sweetener alternatives for safer use.

Sucralose is a widely used artificial sweetener linked to gut microbiome disruption, impaired immune function, DNA damage, metabolic issues, and increased appetite. These adverse effects raise concerns about its safety, prompting caution and consideration of natural sweetener alternatives for better health.

This article reviews current scientific evidence surrounding sucralose, a popular artificial sweetener, and its possible carcinogenic effects. Although regulatory agencies uphold sucralose's safety within recommended limits, recent studies reveal that certain sucralose derivatives may cause DNA damage and gut inflammation linked to cancer. The article offers a comprehensive analysis of research findings, regulatory perspectives, mechanisms involved, and answers frequently asked questions to help readers understand the ongoing debate about sucralose and cancer risk.