Aspartame and xylitol are two distinct sweeteners widely used across various sectors. Aspartame is a calorie-free artificial sweetener composed of amino acids, intensively sweet without calories. Xylitol is a natural sugar alcohol with dental benefits and fewer calories than sugar. Aspartame does not contain xylitol, and both have different uses, health considerations, and safety profiles. Knowing these differences helps manufacturers produce healthier, appealing products and aids consumers in making informed dietary choices.