This article investigates whether artificial sweeteners are inflammatory, analyzing their effects on gut microbiota, immune responses, and inflammation pathways. While some artificial sweeteners may promote intestinal and systemic inflammation, the effects vary by type, dosage, and individual factors. Safer alternatives like natural sweeteners and functional sugar alcohols show promise in reducing sugar intake without harmful inflammatory impacts, empowering consumers to make informed choices for better health.

This article offers a detailed analysis of aspartame's potential to cause inflammation. Scientific research reveals a complex relationship where aspartame may promote or reduce inflammation depending on dose, individual factors, and metabolic health. While generally safe for the broader population within recommended intake, caution is advised for sensitive groups. The industry trend toward natural sweeteners, functional polyols, and fiber-enriched blends aligns with reducing inflammatory risks and enhancing health in food and healthcare products.