Stevia and Splenda are two popular sugar substitutes, each offering unique benefits. Stevia, sourced from natural plant leaves, is favored for its clean-label status, sustainability, and safety for diabetics. Splenda, while highly stable and similar in taste to sugar, is artificial and has potential gut health drawbacks. Stevia's rapid growth in the food and beverage industry and its minimal side effects make it the preferred choice for health-focused manufacturers and consumers alike.