This article explores the relationship between sucralose and dental cavities. Scientific evidence confirms that sucralose is non-cariogenic and does not contribute to tooth decay, unlike sugar which promotes acid production and plaque formation. While some sucralose products contain fermentable bulking agents, pure sucralose is safe for teeth. Acidic sucralose-containing products may erode enamel independently of the sweetener. Overall, sucralose is a safer alternative to sugar for dental health and sugar reduction initiatives.